Evidence from two cohorts for the frailty syndrome as an emergent state of...
AbstractFrailty is a clinical syndrome often present in older adults and characterized by a heightened vulnerability to stressors. The biological antecedents and etiology of frailty are unclear despite...
View ArticleAgreement between standard and self-reported assessments of physical frailty...
AbstractBackgroundThe ability to identify frail older adults using a self-reported version of the physical frailty phenotype (PFP) that has been validated with the standard PFP could facilitate...
View ArticleClinical trial participation predicts improved survival in older adults...
AbstractBackgroundOlder adults represent a large oncologic demographic and are under-represented within oncology research despite constituting nearly two-thirds of the oncologic population in the...
View ArticleSubstitution of self-reported measures for objectively assessed grip strength...
AbstractBackgroundFrailty assessment promises to identify older adults at risk for adverse consequences following stressors and target interventions to improve health outcomes. The Physical Frailty...
View ArticleThe physical frailty syndrome as a transition from homeostatic symphony to...
AbstractFrailty in aging marks a state of decreased reserves resulting in increased vulnerability to adverse outcomes when exposed to stressors. This Perspective synthesizes the evidence on the...
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