Building an identifiable latent class model with covariate effects on...
AbstractIn recent years, latent class models have proven useful for analyzing relationships between measured multiple indicators and covariates of interest. Such models summarize shared features of the...
View ArticleA Diagnostic for Association in Bivariate Survival Models
AbstractWe propose exploratory, easily implemented methods for diagnosing the appropriateness of an underlying copula model for bivariate failure time data, allowing censoring in either or both failure...
View ArticleSurrogate screening models for the low physical activity criterion of frailty
AbstractBackground and aims: Low physical activity, one of five criteria in a validated clinical phenotype of frailty, is assessed by a standardized, semiquantitative questionnaire on up to 20 leisure...
View ArticlePredicting Latent Class Scores for Subsequent Analysis
AbstractLatent class regression models relate covariates and latent constructs such as psychiatric disorders. Though full maximum likelihood estimation is available, estimation is often in three steps:...
View ArticleComparative effectiveness studies to improve clinical outcomes in end stage...
AbstractBackgroundEvidence is lacking to inform providers’ and patients’ decisions about many common treatment strategies for patients with end stage renal disease (ESRD).Methods/designThe DEcIDE...
View ArticleJohns Hopkins University Department of Biostatistics
AbstractThe Johns Hopkins Department of Biostatistics was established in 1918, the first of its kind. This article provides an overview to its key personalities and traditions, and its accomplishments...
View ArticlePatterns in blood pressure medication use in US incident dialysis patients...
AbstractBackgroundSeveral observational studies have evaluated the effect of a single exposure window with blood pressure (BP) medications on outcomes in incident dialysis patients, but whether BP...
View ArticleTrends in anemia management in US hemodialysis patients 2004–2010
AbstractBackgroundThere have been major changes in the management of anemia in US hemodialysis patients in recent years. We sought to determine the influence of clinical trial results, safety...
View ArticleSemicompeting risks in aging research: methods, issues and needs
AbstractA semicompeting risks problem involves two-types of events: a nonterminal and a terminal event (death). Typically, the nonterminal event is the focus of the study, but the terminal event can...
View ArticleAssociation of mitochondrial DNA levels with frailty and all-cause mortality
AbstractMitochondrial function is altered with age and variants in mitochondrial DNA (mtDNA) modulate risk for several age-related disease states. However, the association of mtDNA copy number, a...
View ArticleFrailty: a tale of two concepts
AbstractFrailty is increasingly relevant for clinicians to improve care for vulnerable older adults. Prominent frailty measures include the frailty phenotype and the frailty index. The frailty...
View ArticleThe Role of Religious Involvement in the Relationship Between Early Trauma...
AbstractThe purpose of this study was to determine the role of religious involvement and related indicators - religious coping, intrinsic religiosity, forgiveness and gratitude - in reducing the...
View ArticleThe Internalized Homophobia Scale for Vietnamese Sexual Minority Women:...
AbstractWe developed the first Vietnamese Internalized Homophobia (IH) scale for use with Vietnamese sexual minority women (SMW). Drawing from existing IH scales in the international literature and...
View ArticleAnxiety disorders and all-cause mortality: systematic review and meta-analysis
AbstractPurposeThe purpose of this study was to perform a systematic review and meta-analysis of prospective cohort studies that examined the relationship between anxiety disorders, or clinically...
View ArticleStandard set of health outcome measures for older persons
AbstractBackgroundThe International Consortium for Health Outcomes Measurement (ICHOM) was founded in 2012 to propose consensus-based measurement tools and documentation for different conditions and...
View ArticleA Robust Characterization of Inflamm-Aging and Other Immune Processes Through...
AbstractChronic low-grade inflammation has long been considered an important part of the aging process (“inflamm-aging”). However, measurement of this process is highly variable across studies, often...
View ArticleParametric estimation of association in bivariate failure-time data subject...
AbstractThere has arisen a considerable body of research addressing the estimation of association between paired failure times in the presence of competing risks. In a 2002 paper, Bandeen-Roche and...
View ArticleA Robust Characterization of Inflamm-aging and Other Immune Processes Through...
AbstractChronic low-grade inflammation has long been considered an important part of the aging process (“inflamm-aging”). However, measurement of this process is highly variable across studies, often...
View Article